Organoids reveal how to protect the brain against dementia and ALS following traumatic injury, according to USC Stem Cell study

A traumatic brain injury (TBI) can quadruple your risk for developing dementia, and also increase your chances of developing neurodegenerative diseases such as ALS. In a new study published in Cell Stem Cell, USC scientists use lab-grown human brain structures known as organoids to offer insights into why this is the case and how to Read More…

National Academy of Inventors elects Justin Ichida and three other Keck School of Medicine faculty as senior members

The National Academy of Inventors (NAI), a nonprofit member organization that encourages inventors in higher education, has announced that four researchers from the Keck School of Medicine of USC are part of its 2024 class of senior members. Election as an NAI senior member recognizes remarkable innovation producing technologies that have brought, or aspire to Read More…

Research from Justin Ichida’s lab advances toward clinical development for ALS, following a license agreement between companies Takeda and AcuraStem

USC Stem Cell scientist Justin Ichida has learned to inhabit two worlds: the university where his lab makes discoveries, and the companies that can help commercialize these discoveries into new treatments for neurodegenerative diseases. The first of these potential treatments now has the potential to enter clinical development for patients with amyotrophic lateral sclerosis (ALS), Read More…

ALS and frontotemporal dementia show origins in utero, according to evidence from mice and patient-derived stem cells

Even though neurodegenerative diseases often strike in middle age or later, patients could have structural differences in their brains that arise before birth. In a new study in Cell Reports, USC Stem Cell scientists used both patient-derived nerve cells and laboratory mice to demonstrate that the most common genetic cause of amyotrophic lateral sclerosis (ALS) Read More…

Justin Ichida honored as the inaugural John Douglas French Alzheimer’s Foundation Associate Professor of Stem Cell Biology and Regenerative Medicine at USC

In March 2020, Justin Ichida, PhD, was appointed to a prestigious endowed professorship at Keck School of Medicine of USC through a generous philanthropic gift from the John Douglas French Alzheimer’s Foundation. On October 20, 2022, more than two years later, an appreciative group of scientific leaders, colleagues, philanthropists, family, and friends were at last Read More…