Recent Publications

  1. Shi, Y, Hung, ST, Rocha, G, Lin, S, Linares, GR, Staats, KA et al.. Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons. JCI Insight. 2019;5 :. doi: 10.1172/jci.insight.127736. PubMed PMID:31310593 .
  2. Li, Y, Ichida, JK. Directly Reprogrammed Neurons Still Have Some Growing Up to Do. Cell Stem Cell. 2019;25 (1):1-2. doi: 10.1016/j.stem.2019.06.005. PubMed PMID:31271745 .
  3. Moore, S, Alsop, E, Lorenzini, I, Starr, A, Rabichow, BE, Mendez, E et al.. ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD. Acta Neuropathol. 2019;138 (1):49-65. doi: 10.1007/s00401-019-01999-w. PubMed PMID:30945056 .
  4. Ichida, JK, Staats, KA, Davis-Dusenbery, BN, Clement, K, Galloway, KE, Babos, KN et al.. Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons. Development. 2018;145 (22):. doi: 10.1242/dev.168617. PubMed PMID:30337375 PubMed Central PMC6262794.
  5. Wilkinson, B, Evgrafov, OV, Zheng, D, Hartel, N, Knowles, JA, Graham, NA et al.. Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders. Biol. Psychiatry. 2019;85 (4):305-316. doi: 10.1016/j.biopsych.2018.05.009. PubMed PMID:29961565 PubMed Central PMC6251761.
  6. Kramer, NJ, Haney, MS, Morgens, DW, Jovičić, A, Couthouis, J, Li, A et al.. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nat. Genet. 2018;50 (4):603-612. doi: 10.1038/s41588-018-0070-7. PubMed PMID:29507424 PubMed Central PMC5893388.
  7. Shi, Y, Lin, S, Staats, KA, Li, Y, Chang, WH, Hung, ST et al.. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nat. Med. 2018;24 (3):313-325. doi: 10.1038/nm.4490. PubMed PMID:29400714 PubMed Central PMC6112156.
  8. Patten, SA, Aggad, D, Martinez, J, Tremblay, E, Petrillo, J, Armstrong, GA et al.. Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis. JCI Insight. 2017;2 (22):. doi: 10.1172/jci.insight.97152. PubMed PMID:29202456 PubMed Central PMC5752378.
  9. Kaneda, S, Kawada, J, Akutsu, H, Ichida, J, Ikeuchi, Y, Fujii, T et al.. Compartmentalized embryoid body culture for induction of spatially patterned differentiation. Biomicrofluidics. 2017;11 (4):041101. doi: 10.1063/1.4994989. PubMed PMID:28852428 PubMed Central PMC5552387.
  10. Pepper, JP, Wang, TV, Hennes, V, Sun, SY, Ichida, JK. Human Induced Pluripotent Stem Cell-Derived Motor Neuron Transplant for Neuromuscular Atrophy in a Mouse Model of Sciatic Nerve Injury. JAMA Facial Plast Surg. 2017;19 (3):197-205. doi: 10.1001/jamafacial.2016.1544. PubMed PMID:27978547 PubMed Central PMC5815137.