Shi Y, Lin S, Staats K, Li Y, Chang W-H, Hung S-T, Hendricks E, Linares GR, Wang Y, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Hennes V, Seah C, Nelson AR, Coba M, Zlokovic BV, Ichida JK. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nature Medicine. 2018;24, 313–325. doi:10.1038/nm.4490. PMID: 29400714. [PubMed]
2013
Hanada T, Weitzer S, Mair B, Bernreuther C, Wainger BJ, Ichida J, Hanada R, Orthofer M, Cronin SJ, Komnenovic V, Minis A, Sato F, Mimata H, Yoshimura A, Tamir I, Rainer J, Kofler R, Yaron A, Eggan KC, Woolf CJ, Glatzel M, Herbst R, Martinez J, Penninger JM. CLP1 links tRNA metabolism to progressive motor-neuron loss. Nature. 2013 Mar 28;495(7442):474–80. doi: 10.1038/nature11923. PMID: 23474986. [PubMed] [PDF]
2011
Egli D, Chen AE, Saphier G, Ichida J, Fitzgerald C, Go KJ, Acevedo N, Patel J, Baetscher M, Kearns WG, Goland R, Leibel RL, Melton DA, Eggan K. Reprogramming within hours following nuclear transfer into mouse but not human zygotes. Nature Communications. 2011 Oct 4; 2:488. doi: 10.1038/ncomms1503. PMID: 21971503. [PubMed] [PDF]
Son EY*, Ichida JK*, Wainger BJ, Toma JS, Rafuse VF, Woolf CJ, Eggan K. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell. 2011 Sep 2;9(3):205–18. doi: 10.1016/j.stem.2011.07.014. PMID: 21852222. [PubMed] [PDF]
2010
Ichida JK, Kiskinis E, Eggan K. Shushing down the epigenetic landscape towards stem cell differentiation. Development. 2010 Aug 1;137(15):2455–60. doi: 10.1242/dev.049130. PMID: 20554719. Review. [PubMed] [PDF]
Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA. Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication. J Am Chem Soc. 2010 Apr 28;132(16):5880–5. doi: 10.1021/ja100780p. PMID: 20359213. [PubMed] [PDF]
2009
Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, Egli D, Loh KM, Carter AC, Di Giorgio FP, Koszka K, Huangfu D, Akutsu H, Liu DR, Rubin LL, Eggan K. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell. 2009 Nov 6;5(5):491–503. doi: 10.1016/j.stem.2009.09.012. PMID: 19818703. [PubMed] [PDF]
2005
Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW. High fidelity TNA synthesis by Therminator polymerase. Nucleic Acids Res. 2005 Sep 12;33(16):5219–25. PMID: 16157867. [PubMed] [PDF]
Horhota A, Zou K, Ichida JK, Yu B, Mclaughlin LW, Szostak JW, Chaput JC. Kinetic analysis of an efficient DNA-dependent TNA polymerase. J Am Chem Soc. 2005 May 25;127(20):7427–34. PMID: 15898792. [PubMed] [PDF]
Ichida JK, Zou K, Horhota A, Yu B, McLaughlin LW, Szostak JW. An in vitro selection system for TNA. J Am Chem Soc. 2005 Mar 9;127(9):2802–3. PubMed PMID: 15740086. [PubMed] [PDF]
2003
Chaput JC, Ichida JK, Szostak JW. DNA polymerase-mediated DNA synthesis on a TNA template. J Am Chem Soc. 2003 Jan 29;125(4):856–7. PubMed PMID: 12537469. [PubMed] [PDF]
